Fig. 7.

Solvation profile of the residues in HEWL adsorbed from (a) 0.03 and (b) 1.00 mg/ml on the glass surface. Residue color code: yellow (>threefold decrease in solvent accessibility), blue (>threefold increase in solvent accessibility) and light gray (other residues). The arrows point to the location of the three key amino acid residues that provide the catalytic function of the enzyme (E35, D52, and D101). Reproduced with permission from Thyparambil et al., Acta Biomater. 10, 2404 (2014). Copyright 2014 Elsevier.