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. 2014 Nov 27;37(1):53–59. doi: 10.1007/s11096-014-0038-3

Table 3.

Relative risk estimates for clinical outcomes during and after the first 6 months of warfarin exposure

Clinical outcomes
INR Before 6 months After 6 months
Relative risk p-value Relative risk p-value
ACS
 <2 6.6505 <0.0001 4.3918 <0.0001
 >3 0.8847 0.4645 0.7998 0.5357
Ischemic stroke
 <2 6.8189 <0.0001 2.9368 <0.0001
 >3 0.5362 0.0090 0.4596 0.0967
Transient ischemic attack
 <2 8.9904 <0.0001 1.8577 0.0768
 >3 0.8693 0.7378 0.2505 0.1769
Systemic embolism
 <2 4.8545 <0.0001 4.5573 0.0067
 >3 0.2138 0.0338 1.8882 0.4476
Major bleeding
 <2 2.0007 <0.0001 3.0921 <0.0001
 >3 1.4562 0.0120 1.5150 0.0555

INR 2–3 = Reference group

ACS acute coronary syndrome, INR international normalized ratio