Fig. 2.

Flow cytometry results show apoptosis, determined with the Annexin V test. a Fibroblast-like synoviocytes (FLS) derived from patients with rheumatoid arthritis (RA) were incubated overnight with 20 μM Smac 060 or 066 or tissue medium alone (CTRL). b FLS from patients with osteoarthritis (OA) were incubated overnight with 20 μM Smac 060 or 066 or tissue medium alone (CTRL). Ordinal axes, Annexin⁺ cells; abscissa axes, propidium iodide (PI)⁺ cells. Data are expressed as percentage of Annexin⁺ + Annexin⁺ PI⁺ cells. Data are representative of four independent experiments.