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. 2015 Jan 28;7:3. doi: 10.1186/s13231-014-0012-0

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© Hong et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Representative images of FITC-dextran leakage from rats treated with DHA or saline. FITC-dextran was intravenously injected at 72 h after MCAo and mosaic images at six bregma levels of entire hemisphere, cortical and subcortical areas were obtained from DHA- or vehicle-treated rats. Diffusive leakage of FITC-dextran was observed within infracted areas in the saline treated rat. In contrast, FITC-fluorescence was dramatically diminished by DHA treatment.