Table 1.
Most significant genes changed their expressions in zebrafish exposed to 500 μg/l BDE47 (FC > 10 or FC < 0.1)
| Gene symbol | Accession ID | BLAST | Fold change | Style | Counts_500 | Counts_S |
|---|---|---|---|---|---|---|
| hsp70.2 | XP_003198158 | HSPA8 | 115.04 | up | 23095.632 | 200.760 |
| pth1a | NM_212950 | 112.61 | up | 356.029 | 3.162 | |
| hsp70 | NM_131397 | HSPA8 | 111.46 | up | 21407.932 | 192.066 |
| hsp70l | NM_001113589 | HSPA8 | 75.27 | up | 47595.391 | 632.316 |
| LOC100536983 | XP_003200216 | 56.47 | up | 3123.057 | 55.328 | |
| fosl1a | NM_001161552 | FOSL2 | 53.77 | up | 1997.507 | 37.149 |
| Fosb | NM_001007312 | FOSB | 51.63 | up | 367.272 | 7.114 |
| lepb | NM_001030186 | 49.47 | up | 391.007 | 7.904 | |
| MGC174857 | NM_001103115 | CTSV | 37.93 | up | 59.963 | 1.581 |
| hspb9 | NM_001114705 | 27.69 | up | 7746.431 | 279.800 | |
| il12a | NM_001007107 | 26.87 | up | 42.474 | 1.581 | |
| mmp13a | NM_201503 | MMP13 | 26.62 | up | 3219.247 | 120.930 |
| si:ch211-199o1.2 | NM_001100062 | HSPA1L | 24.38 | up | 1618.993 | 66.393 |
| lepa | NM_001128576 | 23.71 | up | 112.430 | 4.742 | |
| LOC557301 | XP_685429 | CARTPT | 21.11 | up | 5723.939 | 271.105 |
| LOC100538045 | XP_003197928 | 20.55 | up | 32.480 | 1.581 | |
| LOC570404 | XP_698974 | 20.39 | up | 161.150 | 7.904 | |
| MGC174155 | NM_001103118 | CTSV | 18.97 | up | 59.963 | 3.162 |
| si:dkey-26 g8.4 | XP_003199634 | CTSV | 18.97 | up | 59.963 | 3.162 |
| LOC561147 | XP_689643 | PIM1 | 18.97 | up | 44.972 | 2.371 |
| MGC174152 | NM_001105680 | CTSV | 17.12 | up | 81.199 | 4.742 |
| atf3 | NM_200964 | ATF3 | 16.79 | up | 7218.010 | 429.975 |
| LOC100333562 | XP_002666978 | HIST1H4F | 16.60 | up | 26.234 | 1.581 |
| LOC100003896 | NM_001115069 | 16.20 | up | 51.218 | 3.162 | |
| LOC100000332 | XP_002662857 | RNF182 | 15.21 | up | 4148.669 | 272.686 |
| si:ch211-231 m23.4 | XP_002665089 | FFAR3 | 15.01 | up | 23.735 | 1.581 |
| il11b | XP_003200597 | 15.01 | up | 23.735 | 1.581 | |
| si:dkey-239j18.3 | XP_001341714 | CTSV | 15.01 | up | 23.735 | 1.581 |
| LOC100332718 | XP_002666833 | GDPGP1 | 14.75 | up | 34.978 | 2.371 |
| timp2b | NM_213296 | TIMP2 | 14.53 | up | 3892.578 | 267.944 |
| LOC100538016 | XP_003200235 | BTG3 | 14.07 | up | 1000.628 | 71.136 |
| LOC797181 | XP_001337638 | CXCR1 | 13.83 | up | 43.723 | 3.162 |
| LOC561346 | XP_689846 | PIM1 | 13.75 | up | 108.682 | 7.904 |
| LOC100007777 | XP_001346148 | PIM1 | 12.12 | up | 86.196 | 7.114 |
| LOC100334610 | XP_002663270 | 12.05 | up | 228.608 | 18.969 | |
| ifnphi1 | NM_207640 | 11.85 | up | 18.738 | 1.581 | |
| ptrh1 | NM_001013330 | PTRH1 | 11.78 | up | 595.879 | 50.585 |
| mmp9 | NM_213123 | MMP9 | 11.61 | up | 5094.331 | 438.669 |
| insb | NM_001039064 | INS | 11.59 | up | 54.966 | 4.742 |
| sgk2b | NM_001076564 | SGK1 | 11.30 | up | 938.166 | 82.991 |
| si:dkey-85 k15.6 | XP_001344298 | 11.06 | up | 34.978 | 3.162 | |
| LOC100537455 | XP_003199799 | ADTRP | 11.06 | up | 26.234 | 2.371 |
| LOC795066 | XP_001335163 | CASP10 | 10.75 | up | 42.474 | 3.952 |
| LOC100007785 | XP_001920525 | PIM1 | 10.59 | up | 83.698 | 7.904 |
| il1b | NM_212844 | 10.46 | up | 760.777 | 72.716 | |
| ctsl1b | NM_131198 | CTSV | 10.27 | up | 16.240 | 1.581 |
| tcap | XP_684103 | TCAP | 10.22 | up | 4128.682 | 403.892 |
| LOC561283 | XP_001920442 | PIM1 | 10.16 | up | 112.430 | 11.066 |
| cyp2k6 | NM_200509 | CYP2C19 | 10.15 | up | 738.291 | 72.716 |
| LOC100535212 | XP_003199890 | NXF1 | 0.099 | down | 1.249 | 12.646 |
| LOC100537950 | XP_003200691 | 0.099 | down | 1.249 | 12.646 | |
| LOC100151419 | XP_001922180 | IRGC | 0.093 | down | 1.249 | 13.437 |
| LOC794295 | XP_001334228 | CBLN4 | 0.088 | down | 7.495 | 85.363 |
| LOC100536146 | XP_003198781 | TBX5 | 0.053 | down | 1.249 | 23.712 |
| LOC100537396 | XP_003198045 | GIMAP7 | 0.049 | down | 1.249 | 25.293 |
| LOC100538301 | XP_003200448 | TTLL5 | 0.045 | down | 1.249 | 27.664 |
| cyp2aa8 | NM_001006080 | CYP2J2 | 0.040 | down | 2.498 | 63.232 |
| si:dkey-58f10.12 | XP_002662081 | 0.026 | down | 1.249 | 47.424 | |
| aqp8b | NM_001114910 | AQP8 | 0 | down | 0 | 20.550 |
| dicp1.1 | LOC100007383 | 0 | down | 0 | 19.760 | |
| or115-11 | NM_001130806 | OR7C1 | 0 | down | 0 | 18.969 |
| ora3 | XP_002666147 | 0 | down | 0 | 16.598 | |
| LOC100535486 | XP_003198138 | AQP8 | 0 | down | 0 | 14.227 |
| LOC100535815 | XP_003198338 | ZFP2 | 0 | down | 0 | 14.227 |
| LOC567550 | XP_005162589 | G2E3 | 0 | down | 0 | 13.437 |
| aadacl4 | NM_001172642 | AADACL4 | 0 | down | 0 | 12.646 |
| LOC100535879 | XP_003200240 | 0 | down | 0 | 11.856 | |
| LOC796876 | XP_001334272 | CXorf21 | 0 | down | 0 | 11.856 |
| pou5f1 | NM_131112 | POU3F3 | 0 | down | 0 | 11.856 |
| zranb3 | zranb3 | ZRANB3 | 0 | down | 0 | 10.275 |
| LOC566574 | XP_001919203 | GIMAP7 | 0 | down | 0 | 10.275 |