TABLE 2.
Medical History and Treatment of study participants by kidney disease status
| eGFR ≥ 60 | eGFR < 60 | ||||||
|---|---|---|---|---|---|---|---|
| Total (N=2146) | No Albuminuria (N=1217) | Micro Albuminuria (N=365) | Macro Albuminuria (N=121) | No Albuminuria (N=231) | Micro Albuminuria (N=125) | Macro Albuminuria (N=87) | |
| Medical History | |||||||
| Hypertension(%)***††† | 82.4 | 77.9 | 87.3 | 89.2 | 86.5 | 89.4 | 93.0 |
| Laser Treatment for Diabetic Retinopathy/Macular Edema(%)***††† | 3.1 | 1.5 | 4.1 | 4.1 | 3.1 | 12.8 | 5.8 |
| Current Cigarette Smoker (%)††† | 11.9 | 12.6 | 14.5 | 15.7 | 5.6 | 4.8 | 12.6 |
| LVEF*** | 57.4±10.9 | 58.0±10.2 | 57.2±11.2 | 55.0±12.6 | 57.6±11.1 | 56.6±11.5 | 53.1±12.8 |
| Abnormal LVEF (< 50 %) (%)†† | 17.0 | 14.7 | 16.4 | 23.1 | 18.8 | 20.0 | 34.9 |
| Medical Treatment at baseline | |||||||
| ACEI or ARB(%)***††† | 77.2 | 72.0 | 82.4 | 86.0 | 85.3 | 85.6 | 82.8 |
| # BP medications***††† | 2.2±1.0 | 2.0±1.0 | 2.4±1.0 | 2.6±1.1 | 2.4±1.0 | 2.6±0.9 | 2.8±1.2 |
| Statins(%) | 74.2 | 72.9 | 76.9 | 76.0 | 73.6 | 76.0 | 78.2 |
| Glucose Control | |||||||
| Diet Alone (%)*** | 8.7 | 10.5 | 4.4 | 3.3 | 12.1 | 6.4 | 2.3 |
| Oral Hypoglycemic Agent (%)††† | 80.5 | 81.9 | 84.7 | 77.7 | 77.5 | 69.6 | 70.9 |
| Insulin(%)***††† | 27.3 | 21.5 | 32.1 | 38.8 | 24.2 | 44.8 | 54.0 |
Abbreviations: eGFR (estimated glomerular filtration rate) LVEF (left ventricular ejection fraction)
*
indicates trend comparison among albuminuria status categories (none, microalbuminuria, macroalbuminuria),
*
p < 0.05,
**
p < 0.01,
***
p < 0.001
†
indicates comparison between GFR categories (GFR < 60, GFR ≥ 60)
†
p < 0.05,
††
p < 0.01,
†††
p < 0.001