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. Author manuscript; available in PMC: 2015 Jan 31.
Published in final edited form as: Am J Med Sci. 2010 May;339(5):401–410. doi: 10.1097/MAJ.0b013e3181d430ad

Table 4.

Factors Associated with More Severe Albuminuria Status

N = 2030 Univariate Multivariable**
Odds Ratio*** (95% CI) p_value Odds Ratio*** (95% CI) p_value
Age 1.01 (1.0–1.02) 0.09 0.99 (0.97–1.00) 0.29
Female 1.10 (0.90–1.34) NS 0.81 (0.64–1.03) 0.09
Race/Ethnicity 0.001 0.028
 White Non-Hispanic ---- -----
 Black Non-Hispanic 1.56 (1.23–1.99) 1.18 (0.89–1.56)
 Other Non-Hispanic 1.30 (0.86–1.97) 1.41 (0.90–2.20)
 Hispanic 1.36 (1.03–1.79) 1.53 (1.13–2.07)
Smoking Status 0.002
 Never Smoked --- ---
 Current Smoker 1.29 (0.95–1.76) 0.11 1.75 (1.22–2.5)
 Former Smoker 1.24 (1.01–1.53) 0.04 1.45 (1.14–1.83)
Duration of diabetes (every 5 years) 1.26 (1.20–1.33) < 0.001 1.20 (1.13–1.27) < 0.001
Non-Coronary Artery Disease* 1.74 (1.41–2.13) < 0.001 1.31 (1.04–1.64) 0.02
Lower extremity ulcer 2.88 (1.62–5.13) < 0.001 2.18 (1.15–4.12) 0.02
Systolic BP (every 10 mmHG) 1.33 (1.27–1.39) < 0.001 1.36 (1.29–1.43) <0.001
Number of Hypertension Drugs 1.56 (1.42–1.71) < 0.001 1.42 (1.29–1.58) 0.005
HgbA1c 1.25 (1.18–1.32) < 0.001 1.25 (1.18–1.34) <0.001
Log(Triglycerides) 1.28 (1.09–1.50) < 0.001 1.31 (1.10–1.57) 0.003
LVEF
 Normal LVEF (≥ 50) --- ----
 Abnormal LVEF** 1.61 (1.27–2.04) < 0.001 1.46 (1.12–1.89) 0.005
 Unknown LVEF 1.30 (0.78–2.16) NS 1.27 (0.73–2.20) NS
Reduced eGFR 2.36 (1.90–2.92) < 0.001 2.24 (1.75–2.85) < 0.001

Abbreviations: eGFR (estimated glomerular filtration rate), LVEF (left ventricular ejection fraction) CI(confidence interval), NS (not significant)

*

Non-Coronary Artery Disease includes documented carotid disease, carotid surgery, carotid stent, non-coronary vascular surgery, or intermittent claudication.

**

All variables listed included in the ordinal logistic mode.

***

Odds Ratio of More Severe Albuminuria Status compared to less severe