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. Author manuscript; available in PMC: 2015 Jan 31.
Published in final edited form as: Am J Med Sci. 2010 May;339(5):401–410. doi: 10.1097/MAJ.0b013e3181d430ad

Table 6.

Factors Associated with Multivariate Analysis of Albuminuric Status and reduced eGFR

N = 2030 OR for Albuminuria (ACR > 30) OR for reduced eGFR (eGFR < 60) Global test for significance p-value for equality between albuminuria OR and reduced eGFR OR
Smoking Status <0.001 0.02
 Current Smoker vs never 1.63* 0.51**
 Former Smoker vs never 1.42** 1.02
Non-coronary Artery Disease 1.36* 1.35* 0.006 0.95
Lower extremity ulcer 2.97** 1.25 0.01 0.06
Systolic BP, per 10 mmHG increase 1.32*** 1.03 <0.001 <0.001
Number of Hypertension Drug Classes, per 1 drug class increase 1.43*** 1.36*** <0.001 0.52
Duration of Diabetes, per 5 years 1.14*** 1.23*** <0.001 0.11
Diabetes Drugs <0.001 0.001
 2 or more drug classes vs 0,1 drug class 1.57** 0.80
 Insulin vs 0,1 drug classes 1.82*** 1.12
HgbA1c per 1% increase 1.19*** 0.81*** <0.001 <0.001
HDL, per 5 mg/dl increase 1.04 0.95 0.13 0.04
Ln(Triglycerides) 1.43*** 1.27* <0.001 0.41
LV Ejection Fraction
 Abnormal (EF < 50%) 1.42* 1.48** 0.004 0.84

Abbreviations: eGFR (estimated glomerular filtration rate), LV (left ventricular), OR(odds ratio)

Model also included age, race/ethnicity, and gender for the albuminuria outcome. An indicator variable for missing LV Ejection Fraction was also included.

*

p <0.05,

**

p < 0.01,

***

p < 0.001