Table 2.
Findings of ischemic, hemorrhagic and vascular pathology, according to the groups at the clinical enrollment
| Control (n=14) | CVD risk (n=17) |
DAT (n=26) | p value* | |||
|---|---|---|---|---|---|---|
| SHEP (n=11) | CS (n=6) | |||||
| Vascular pathology | ||||||
| Large artery cerebralinfarcts | 1 (7.14%) | 3 (17.65%) | 1 (9.09%) | 2 (33.33%) | 2 (7.69%) | 0.5 44 |
| Cortical microinfarcts | 5 (35.71%) | 5 (29.41%) | 2 (18.18%) | 3 (50.00%) | 5 (19.23%) | 0.550 |
| Lacunes | 5 (35.71%) | 6 (35.29%) | 3 (27.27%) | 3 (50.00%) | 8 (30.77%) | 0.933 |
| Cerebral hemorrhages | 1 (7.14%) | 2 (11.76%) | 1 (9.09%) | 1 (16.67%) | 5 (19.23%) | 0.627 |
| Subcortical arteriosclerotic leukoencephalopathy | 0 (0.00%) | 1 (5.88%) | 0 (0.00%) | 1 (16.67%) | 1 (3.85%) | 0.675 |
| Atherosclerosis (of the circle of Willis) | 14 (100.00%) | 16 (94.12%) | 10 (90.91%) | 6 (100.00%) | 22 (84.62%) | 0.307 |
| Arteriosclerosis | 14 (100.00%) | 17 (100.00%) | 11 (100.00%) | 6 (100.00%) | 25 (96.15%) | 0.551 |
| Cerebral amyloid angiopathy | 11 (78.57%) | 9 (52.94%) | 7 (63.64%) | 2 (33.33%) | 22 (84.62%) | 0.071 |
| AD pathology | 6 (42.867%) | 3 (17.65%) | 2 (18.18%) | 1 (16.67%) | 21 (80.77%) | |
Values are presented as number (percentage).
*
Comparisons among the groups on clinical enrollment by using the Fisher's exact test.
Age upon clinical evaluation and the duration to death were adjusted for the analyses.
CVD, cerebrovascular disease; SHEP, Systolic Hypertension in the Elderly Program; CS, Carotid stenosis; DAT, dementia of the Alzheimer type; AD, Alzheimer's disease.