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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Am J Obstet Gynecol. 2014 Aug 8;212(2):208.e1–208.e8. doi: 10.1016/j.ajog.2014.08.007

Figure 1. Oxidative stress biomarker concentrations across pregnancy.

Figure 1

Predicted values (95% confidence intervals) of specific gravity-corrected urinary oxidative stress biomarker concentrations by gestational age at sample collection from generalized additive models adjusted for random intercepts only. Biomarker concentrations at visits 1 (V1; median 10 weeks gestation), 2 (V2; median 15 weeks gestation), 3 (V3; median 26 weeks gestation), and 4 (V4; median 35 weeks gestation) plotted for reference. *Denotes significant difference (p<0.05) in urinary biomarker concentration for the respective visit compared to visit 1, tested using linear mixed model with random intercepts only. Abbreviations: 8-OHdG, 8-hydroxydeoxyguanosine.