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. Author manuscript; available in PMC: 2015 Aug 21.
Published in final edited form as: Nanoscale. 2014 Jul 8;6(16):9742–9751. doi: 10.1039/c4nr01510j

Figure 1. Synthesis of siRNA-loaded NPs by MHF.

Figure 1

(A) Photographs of the MF chip. The device consisted of three inlet ports and one outlet port. The inlet ports were connected to sterile syringes containing either cationic NPs or siRNA buffer solution. (B) Schematics for flow patterns T1 and T2. The effects of flow patterns and flow rates on the particle size of Tf-NP-siRNA for DC-Chol based NPs (C) and DOTMA, DODMA based NPs (D), respectively. Results are presented as mean ± SD of three independent experiments.