Table 4.
Risk of cardiovascular events by electrocardiographic left ventricular hypertrophy (ECG-LVH) status
| ECG-LVH status |
Participants/ events (n) |
Person- years |
Event rate (95% CI) per 10000 person-years |
Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|---|---|---|
| HR (95% CI) | p-value | HR (95% CI) | p-value | HR (95% CI) | p-value | ||||
| True Negative | 4026/267 | 30809 | 8.67 (7.69, 9.77) | Reference | -- | Reference | Reference | -- | |
| True positive | 111/18 | 749 | 24.04 (15.14, 38.15) | 2.79 (1.73, 4.49) | <0.001 | 2.58 (1.54, 4.33) | <0.001 | 1.77 (1.03, 3.04) | 0.038 |
| False positive | 207/14 | 1569 | 8.92(5.29, 15.07) | 1.03 (0.60, 1.77) | 0.909 | 1.28 (0.74, 2.20) | 0.379 | 1.20 (0.69, 2.09) | 0.517 |
| False negative | 386/42 | 2756 | 15.24 (11.26, 20.62) | 1.76 (1.27, 2.43) | <0.001 | 1.83 (1.31, 2.56) | <0.001 | 1.38 (0.98, 1.96) | 0.069 |
Left ventricular hypertrophy by magnetic resonance imaging (MRI-LVH) was used as the gold standard
Model 1: Unadjusted
Model 2 adjusted for socio-demographic characteristics [age, sex, race and socioeconomic status]
Model 3 adjusted for model 1 plus clinical and anthropometric variables [body mass index, systolic blood pressure, blood pressure lowering drugs, diabetes, total cholesterol, lipid lowering drugs and smoking status]