. Author manuscript; available in PMC: 2016 Jan 1.

Published in final edited form as: Biochim Biophys Acta. 2014 Oct 28;1855(1):24–42. doi: 10.1016/j.bbcan.2014.10.005

Table 3.

Cell-free miRNAs secreted by stromal cells

miRNA	Cell of origin	Activity	Targets	Reference
miR-143 (exo)	PCa cells	Inhibits cell proliferation in vitro and tumor growth in vivo		[271]
miR-127, miR-197, miR-222, miR-223 (exo)	BMSC	Induce dormancy in metastatic cells	CXCL12	[298]
miR-223 (exo)	TAMs	Enhances invasion, migration, metastasis in vivo	MF2C	[300]
miR-16, miR-378	Unknown (OCs?)	Unknown		[8]
miR-23b (exo)	BM-MSCs	Inhibit proliferation in vitro, tumor growth in vivo, induce dormancy	MARCS	[299]

BMSC, Bone marrow stem cell; BM-MSC, Bone marrow mesenchymal stem cell; exo, exosomal; OC, osteoclast; PCa, prostate cancer; TAM, tumor-associated macrophage