Table 3.
Differences in means between groups for neurocognitive measures and neuroimaging volumes.
Neurocognitive Measures | MPS II [Age<25] - Control (95% CI) | P-value |
---|---|---|
IQ | −13.83 (−24.25, − 3.41) | 0.012 |
Errors of omission | −8.29 (−24.07, 7.48) | 0.274 |
Errors of commission | −6.23 (−19.43, 6.98) | 0.338 |
Variability (VAR) | −17.52 (−35.32, 0.27) | 0.053 |
Reaction time (RT) | −7.64 (−25.53, 10.25) | 0.376 |
| ||
Neuroimaging Volumes (mL) | ||
| ||
Corpus callosum (CC) | −0.66 (−0.96, −0.35) | <0.001 |
Cortical white matter (WM) | 3.66 (−26.67, 33.99) | 0.807 |
Cortical gray matter (GM) | 19.51 (−16.13, 55.14) | 0.267 |
Frontal lobes (FL) | 9.71 (−3.67, 23.09) | 0.146 |