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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: J Steroid Biochem Mol Biol. 2014 Aug 1;148:290–297. doi: 10.1016/j.jsbmb.2014.07.013

Figure 1. Expression of the vitamin D intracrine system and antibacterial cathelicidin in monocytes cultured in serum from HIV+ and HIV- patients.

Figure 1

Human monocytes from normal healthy donors were cultured in serum (10%) from age-matched HIV+ or HIV- donors in the presence or absence of a toll-like receptor 2/1 ligand (TLR2/1L), PAM3CysK for 24 hrs. Total RNA from these cultures was then used to assess expression of: mRNA for CYP27B1, VDR, CYP24A1, and CAMP. Data are shown as fold-change in TLR2/1L-treated cells relative to vehicle-treated controls cells for each gene ± SE. * = HIV+ statistically different from HIV- subjects, p<0.05; ** p<0.01.