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. 2014 Dec 6;6(2):88–100. doi: 10.1007/s13238-014-0119-z

Figure 4.

Figure 4

Signal pathways in cancers caused by iron excess. A variety of signal pathways are activated in multiple cancer types. These pathways mainly include p53 pathway, Wnt pathway, HIF pathway, DNA replication and repair pathway, cyclins and cell cycle regulation, and oxidative stress pathways