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. Author manuscript; available in PMC: 2015 Feb 2.
Published in final edited form as: Arch Toxicol. 2012 Aug 8;87(1):189–196. doi: 10.1007/s00204-012-0911-6

Fig. 5.

Fig. 5

Apoptosis induced by FA in PD20 and PD20-D2 cells.

(A) Apoptosis in FA-treated PD20 and PD20-D2 cells as a percentage of untreated control cells. FA induced apoptosis in a dose-dependent manner in both cell lines (Ptrend (PD20) < 0.0001 and P trend (PD20-D2) < 0.001) with greater effects in PD20 cells (P(PD20 vs PD20-D2) < 0.01).

(B) Apoptosis-related protein expression in FA-treated PD20 and PD20-D2 cells as a percentage of untreated control cells. p53 was activated and caspase signaling pathway was induced by FA at similar levels in both PD20 and PD20-D2 cells. β-actin is used as loading control.