TABLE 2.
Tidal Breathing, Multiple Breath Washout and Exhaled Nitric Oxide Measurements
| Tidal breathing | Number (n) | Mean (SD) | Median (IQR) | 95% limits of agreement | Median (IQR) intra-subject CV1 |
|---|---|---|---|---|---|
| Tidal volume (ml) | 19 | 30.5 (5.8) | 30.2 (25.3; 34.4) | 18.9 to 42.1 | 6.8 (6; 7.9) |
| Respiratory rate breaths per min | 19 | 49.4 (8.4) | 49.6 (42.9; 54.8) | 41 to 65.9 | 7.7 (6.5; 9.3) |
| Minute ventilation (ml/min) | 19 | 1,487.4 (319.8) | 1,433.5 (1,275.3; 1,634.7) | 860.6 to 2,114.2 | 6.5 (4.6; 8.3) |
| PTEF/TE2 | 19 | 37 (11.5) | 35 (27; 44.8) | 7.46 to 34.26 | 19.7 (15.6; 25.2) |
| MTIF3 | 19 | 54.8 (10.2) | 54.3 (50; 57.3) | 34.9 to 74.7 | 6.6 (5.4;10) |
| MTEF4 | 19 | 46 (12) | 45.8 (36.2; 52) | 22.3 to 69.7 | 7.8 (6.2; 10) |
| Multiple breath washout | Number (n) | Mean (SD) | Median (IQR) | 95% limits of agreement | Median (IQR) intra-subject CV1 |
|---|---|---|---|---|---|
| FRC5 (ml) | 18 | 70.7 (13) | 66.3 (61; 83) | 45.2 to 96.2 | 6.8 (4.5; 8.8) |
| LCI6 | 18 | 7.6 (0.5) | 7.5 (7.3; 7.8) | 6.6 to 8.6 | 3.6 (1.6; 6.4) |
| Moment ratio m1/m0 | 18 | 1.5 (0.1) | 1.5 (1.3; 1.6) | 1.3 to 1.7 | |
| Moment ratio m2/m0 | 18 | 5.6 (0.8) | 5.8 (4.2; 6.6) | 4 to 7.2 |
| Exhaled nitric oxide | Number (n) | Mean (SD) | Median (IQR) | 95% limits of agreement | Median (IQR) intra-subject CV1 |
|---|---|---|---|---|---|
| NO ppb | 19 | 10.4 (7.3) | 9.7 (3.4; 17.2) | −4 to 24.7 | 4.2 (3.3; 5.5) |
| NO output (mcl/sec) | 19 | 7.8 (2.2) | 7.2 (6.2; 9.1) | 3.5 to 12.1 | 2.3 (0.8;3) |
1
Coefficient of variation.
2
Ratio of time to peak tidal expiratory flow over total expiratory time.
3
Mean tidal inspiratory flow.
4
Mean tidal expiratory flow.
5
Functional residual capacity.
6
Lung clearance index.