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. 2015 Jan 20;5(1):e497. doi: 10.1038/tp.2014.137

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Increased amygdala activation during reappraisal for BD patients (a) and relatives (b) compared with their respective controls as well as % signal change in the left amygdala. The difference in % signal change between the reappraisal and view conditions correlated negatively with habitual reappraisal use in the CERQ (c), which was also decreased in BD patients and relatives (d). BD, bipolar disorder; CERQ, Cognitive Emotion Regulation Questionnaire; Con, control; Rel, relative.