Table 2.
Cell-class specific spiking characteristics of pallidal neurons persist following HVC lesion
| GPi | GPi (No HVC) | GPe | GPe (No HVC) | |
|---|---|---|---|---|
| Rate, nonsinging, Hz | 119.5 ± 48.0 | 122.1 ± 27.8 | 113.5 ± 28.8 | 108.2 ± 37.6 |
| Rate, singing, Hz | 263.1 ± 67.5 | 249.2 ± 58.3 | 125.5 ± 33.3 | 152.3 ± 49.3 |
| CV, nonsinging | 0.33 ± 0.13 | 0.30 ± 0.09 | 0.36 ± 0.08 | 0.36 ± 0.10 |
| CV, singing | 0.50 ± 0.10 | 0.43 ± 0.09 | 0.87 ± 0.27 | 0.85 ± 0.35 |
| 99th percentile ISI, nonsinging, ms | 16.4 ± 6.8 | 15.5 ± 6.7 | 20.2 ± 7.8 | 22.9 ± 11.7 |
| 99th percentile ISI, singing, ms | 11.2 ± 4.4 | 12.1 ± 5.6 | 42.5 ± 30.0 | 34.9 ± 22.5 |
| Peak in smoothed firing rate (range: min–max) | 195 ± 21 (153–228) | 189 ± 28 (151–249) | 404 ± 88 (266–583) | 404 ± 112 (253–587) |
Values are means ± SD across cells within a cell class. Singing-related changes in firing rates and interspike interval (ISI) statistics were not affected by HVC lesion. The peak in the smoothed instantaneous firing rate, the metric used to distinguish GPe- from GPi-like neurons, was also not affected (see materials and methods).
CV, coefficient of variation.