Table 1.

Characteristics Associated with Gene Classes

Gene class	Gene examples	Activating transcription factors	Promoter characteristics	Nucleosome remodeling	Basal RNA Pol II association
Primary response genes	TNF, PTGS2, CXCL1/2	NFκB	CpG island promoters	None, low nucleosome occupancy	Yes
	IL1α/β, IL123a, Ccl3	NFκB	Non CpG island promoters	None, low nucleosome occupancy	No
Late primary response genes	Vcam1, Ccl2, IL10	NFκB	Non CpG island promoters	SWI/SNF-dependent	No
	IFIT 1/2/3, Ccl5/12	NFκB	Non CpG island promoters, IRF3 dependent	SWI/SNF-dependent	No
Secondary response genes	IRF7, IL6, IL12b, Nos2	NFκB, Cebpδ	Non CpG island promoters	SWI/SNF-dependent	No