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Maximum percent change from baseline in bALP by use of bisphosphonates
| Sotatercept dose group |
||||
|---|---|---|---|---|
| Parameter | Placebo (n = 6) | 0·1 mg/kg (n = 8) | 0·3 mg/kg (n = 8) | 0·5 mg/kg (n = 8) |
| No bisphosphonates | ||||
| n | 3 | 4 | 6 | 4 |
| bALP, max. mean change from baseline (%) | 39·2 | 22·7 | 36·9 | 104·4 |
| Bisphosphonates | ||||
| n | 3 | 4 | 2 | 4 |
| bALP, max. mean change from baseline (%) | 25·6 | 348·5 | 11·3 | 6·6 |
bALP, bone-specific alkaline phosphatase.
