Table 5.
Characteristics of and probability (odds ratios, OR, with 95% confidence intervals, CI) of invasive breast cancer in women with symptoms1 (lump or retraction only) compared to women with no symptoms at screen
| Tumor characteristics | Total | Symptoms (lump or retraction) | OR (95% CI)*adjusted with age |
|---|---|---|---|
| Size in histology | |||
| Less than 20 mm | 3,841 | 311 (8.1 %) | 2.84 (2.53–3.19) |
| 20–150 mm | 1,340 | 294 (21.9 %) | 9.20 (8.08–10.5) |
| Missing2 | 360 | 47 (13.6 %) | |
| Total | 5,541 | 652 (11.8%) | 4.31 (3.96–4.69) |
| Grade | |||
| Well differentiated | 1,570 | 142 (9.05%) | 3.18 (2.68–3.78) |
| Moderately differentiated | 2,520 | 302 (12.0%) | 4.39 (3.89–4.95) |
| Poorly differentiated | 1,140 | 177 (15.5%) | 5.91 (5.03–6.94) |
| Missing2 | 311 | 31 (10.0%) | |
| Total | 5,541 | 652 (11.8%) | 4.37 (4.02–4.76) |
| pN | |||
| pN0 | 3,533 | 340 (9.6%) | 3.42 (3.06–3.83) |
| pN1+ | 1,601 | 267 (16.7%) | 6.47 (5.67–7.38) |
| pNX | 40 | 4 (10.0%) | 3.56 (1.27–10.0) |
| Missing2 | 367 | 41 (11.2%) | |
| Total | 5,541 | 652 (11.8%) | 4.34 (3.99–4.73) |
| pM | |||
| pM0 | 4,213 | 484 (11.5%) | 4.20 (3.81–4.62) |
| pM1 | 32 | 7 (21.9%) | 9.04 (3.91–20.9) |
| pMX | 772 | 109 (14.1%) | 5.29 (4.32–6.48) |
| Missing2 | 5,24 | 52 (9.9%) | |
| Total | 5,541 | 652 (11.8%) | 4.41 (4.04–4.80) |
1
Symptoms include women, radiographer reported or both.
2
Missing cases here are those referred for further assessment but with missing histological confirmation.
Abbreviations: pN: regional lymph nodes; pN0: no regional lymph node metastasis; pN1+: metastasis with ipsilateral lymph nodes; pNX: regional lymph nodes cannot be assessed; pM: distant metastases; pM0: no distant metastases; pM1: distant metastases; pMX: distant metastases cannot be assessed.