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Hemodynamic effects of l-NAME (50 mg·kg−1·day−1, n = 8) and ANG II (500 ng·kg−1·day−1, n = 7) in conscious chronically instrumented rats. ANG II led to a significant ∼1.5-fold greater increase in mean arterial pressure (MAP; A) and ∼2-fold greater increase in renal vascular resistance (RVR; B), which resulted in an ∼1.5-fold greater decrease in renal blood flow (RBF; C). Values are expressed as means ± SE. *P < 0.05 vs. the respective baseline; #P < 0.05 vs. l-NAME.
