Fig. 2.
Vigilance state time during the baseline period. A: time spent in wake, NREM, and REM sleep during the 24-h baseline period. TrkB.T1 knockout mice spend significantly more time in REM sleep compared with wild-type siblings (Mann-Whitney U-test, *P < 0.05). Wake (B), NREM (C) and REM (D) sleep time across the baseline period, analyzed in 2-h bins. D: two-way repeated-measures ANOVA with factors “genotype” and “time” revealed that knockout mice spend significantly more time in REM than wild-type mice [Fgenotype(1,17) = 5.867; P = 0.027]. White and black bars at top represent the light-dark cycle. Values are expressed as means ± SE.