Table 1.

Vigilance state time and bout duration in TrkB.T1 knockout and wild-type mice

	Time (% Recording)		Bout Duration (Minutes)		Bouts (Count)
	L	D	L	D	L	D
Baseline
Total Sleep
WT	65.4 ± 1.1	19.7 ± 1.9	19.2 ± 2.7	12.7 ± 2.3	28.6 ± 3.9	13.8 ± 2.3
KO	65.5 ± 1.7	21.8 ± 1.3	17.0 ± 2.5	9.0 ± 1.0	34.5 ± 6.0	20.3 ± 3.7
Wake
WT	34.6 ± 1.1	80.3 ± 1.9	7.7 ± 1.0	51.2 ± 17.1	30.8 ± 4.0	16.2 ± 2.7
KO	34.5 ± 1.7	78.2 ± 1.3	6.5 ± 0.7	30.4 ± 4.4	37.6 ± 5.9	22.1 ± 3.7
NREM
WT	58.2 ± 1.0	18.3 ± 1.8	7.5 ± 0.4	7.8 ± 0.6	56.6 ± 2.7	17.9 ± 2.2
KO	57.3 ± 1.6	20.1 ± 1.3	7.1 ± 0.5	6.4 ± 0.5	60.6 ± 4.4	24.2 ± 3.1
REM
WT	7.2 ± 0.3*	1.4 ± 0.2	1.4 ± 0.1	1.5 ± 0.1	37.2 ± 1.8	7.1 ± 0.8
KO	8.2 ± 0.3*	1.7 ± 0.2	1.5 ± 0.0	1.5 ± 0.1	38.8 ± 1.7	7.7 ± 0.8
Recovery
Total Sleep
WT	70.4 ± 1.0	29.1 ± 2.2	24.0 ± 2.6	10.9 ± 0.8	11.3 ± 1.2	19.6 ± 1.8
KO	72.5 ± 2.1	33.3 ± 3.1	21.2 ± 3.0	11.4 ± 1.1	14.1 ± 1.8	23.4 ± 3.8
Wake
WT	29.6 ± 1.0	70.9 ± 2.2	8.0 ± 0.7	20.3 ± 1.7	12.1 ± 1.2	21.4 ± 1.7
KO	27.5 ± 2.1	66.7 ± 3.1	6.4 ± 0.8	20.7 ± 4.0	15.0 ± 2.0	25.9 ± 3.7
NREM
WT	61.7 ± 1.1	26.3 ± 2.0	7.8 ± 0.3	6.3 ± 0.2	28.2 ± 0.7	29.8 ± 2.1
KO	62.8 ± 1.9	29.5 ± 2.8	7.3 ± 0.3	6.4 ± 0.2	30.9 ± 1.6	33.5 ± 3.7
REM
WT	8.8 ± 0.2	2.8 ± 0.2*	1.5 ± 0.1	1.3 ± 0.1*	21.4 ± 0.7	15.4 ± 1.2
KO	9.7 ± 0.4	3.8 ± 0.3*	1.5 ± 0.1	1.5 ± 0.1*	22.8 ± 1.3	17.9 ± 1.5

Values are expressed as means ± SE. Sleep parameters were determined by polysomnography during a baseline recording and during recovery from sleep deprivation.

L, light cycle; D, dark cycle; WT, wild-type (n = 9); KO, TrkB.T1 knockout (n = 10).

^*P < 0.05 between WT and KO values, Mann-Whitney U-test.