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. Author manuscript; available in PMC: 2015 Feb 2.
Published in final edited form as: Acta Neuropathol. 2013 Jan 5;125(3):359–371. doi: 10.1007/s00401-012-1077-2

Figure 4. MXI1 and IL8 methylation are poor prognosis biomarkers in non-WNT medulloblastomas.

Figure 4

a. Distributions of methylation across subgroups for MXI1 and IL8 probes. Black line at β=0.67 shows binary cut-off used for assessment of prognostic relationships. b. Prognostic relationships of MXI1 and IL8 as binary and continuous variables in univariate and multivariate Cox proportional hazard models of non-WNT patients (n=163). CI, confidence interval. c. Binary classification of MXI1 and IL8 is prognostic in log-rank tests of non-WNT patients (n=163). Kaplan-Meier plots show survival curves. Bar plots to right of curve show binary distribution. Methylated tumors, blue; unmethylated tumors, red. At-risk tables are shown below each curve.