Table 1. Demographic data and plasma brain-derived neurotrophic factor baseline levels of heroin-dependent patients and healthy controls.
| Healthy Controls | Heroin-Dependent Patients | |||
|---|---|---|---|---|
| Participant Characteristics | n = 102 | n = 172 | χ2/t/F | p |
| Gender (M/F) | 78/24 | 141/31 | χ2 = 1.21 | 0.279a |
| Age (years) | 32.1 ± 7.0 | 37.0 ± 7.3 | t = −5.495 | <0.0001b |
| Body weight (kg) | 67.2 ± 13.2 | 66.6 ± 12.6 | t = 0.437 | 0.662b |
| Plasma BDNF (ng/mL) | 18.6 ± 9.4 | 10.1 ± 7.7 | F = 52.28 | <0.0001c |
| Heroin-dependency duration (years) | − | 8.2 ± 7.0 | ||
| Methadone oral dose (mg) | − | 35.6 ± 21.3 | ||
| Plasma methadone (ng/mL) | − | 149.1 ± 167.9 | ||
| Urine test morphine-positive (n) | − | 124 | ||
| Urine test methamphetamine-positive(n) | − | 28 |
Data are means ± standard deviation (SD). All patient data were compared with data from healthy controls.
BDNF, brain-derived neurotrophic factor.
aχ2 test;
bindependent samples t test;
canalysis of covariance (ANCOVA): covariate = age.