Table 2.

Pathogenesis in dairy goats and pigs infected with O Manisa-FG virus rescued from cDNA of FMDV, O Manisa strain

FMDV, foot-and-mouth disease virus; qRT-PCR, quantitative reverse transcription-polymerase chain reaction; ID, intradermal; IM, intramuscular; nd, not detected.

^a)Clinical score was determined by adding the following points: an elevated body temperature of 40℃ (1 point), 40.5° (2 points), or 41° (3 points); reduced appetite (1 point) or no food intake and food left over from the day before (2 points); lameness (1 point) or reluctance to stand (2 points); presence of heat and pain after palpation of the coronary band (1 point) or not standing on the affected foot (2 points); vesicles on the feet dependent on the number of feet affected and with a maximum of 4 points; visible mouth lesions on the tongue (1 point), gums or lips (1 point), or snout (1 point), for a maximum of 3 points.

^b)Lesion detected only on the injected foot site.