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. 2015 Jan 30;4(1):68–74. doi: 10.7774/cevr.2015.4.1.68

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© Korean Vaccine Society.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 1 — Enzyme-linked immunospot assay for rabies specific interferon-γ (IFN-γ) (A) and interleukin-4 (IL-4) (B) producing T cells in peripheral blood mononuclear cells (PBMCs), seven days after pre-exposure primary intradermal (ID) vaccination and after ID booster dose. (C) Rapid fluorescent focus inhibition test assay results for rabies virus neutralizing antibody (RVNA) titers in serum, seven days after primary ID vaccination and after ID booster dose. SFC, spot-forming cell. ^**p < 0.005 and ^***p < 0.001 (Mann Whitney test). Pearson's correlation co-efficient analysis of antibody titres and cellular cytokine responses between naive, ID pre-exposure prime and boost groups. (D) RVNA versus IFN-γ. (E) RVNA versus IL-4.