TABLE 2.
Use of anidulafungin to predict susceptibility patterns of caspofungin, using 4,290 clinical isolates of Candida spp. from a global surveillance programa
| Species (no. tested) | Anidulafungin category | No. (%) in caspofungin category |
||
|---|---|---|---|---|
| S | I | R | ||
| C. albicans (2,307) | S | 2,282 (98.9) | 10 (0.4) | 3 (0.1) |
| I | 9 (0.1) | 1 (0.1) | ||
| R | 7 (0.3) | 3 (0.1) | ||
| C. glabrata (655) | S | 576 (87.9) | 4 (0.6) | 3 (0.5) |
| I | 23 (3.5) | 2 (0.3) | 5 (0.8) | |
| R | 2 (0.3) | 4 (0.6) | 36 (5.5) | |
| C. parapsilosis (539) | S | 496 (92.0) | 1 (0.2) | |
| I | 42 (7.8) | |||
| R | ||||
| C. tropicalis (515) | S | 508 (98.6) | ||
| I | 1 (0.2) | 1 (0.2) | ||
| R | 1(0.2) | 4 (0.8) | ||
| C. krusei (124) | S | 114 (91.9) | 6 (4.8) | |
| I | 3 (2.5) | |||
| R | 1 (0.8) | |||
| C. guilliermondii (64) | S | 58 (90.6) | 1 (1.6) | |
| I | 3 (4.7) | 2 (3.1) | ||
| R | ||||
| C. lusitaniae (57) | WT | 56 (98.2) | 1 (1.8) | |
| Non-WT | ||||
| C. kefyr (29) | WT | 27 (93.1) | ||
| Non-WT | 2 (6.9) | |||
a
MIC interpretive criteria for each species as shown in reference 23. Abbreviations: S, susceptible; I, intermediate; R, resistant; WT, wild type; non-WT, non-wild type.