TABLE 1.
Performance of the Alere i Influenza A&B on VTM specimens compared to reference results
| Virus | Genotype | No. detected (Alere/reference)a |
Sensitivity (%) (95% CI) | Specificity (%) (95% CI) | Discordance P value | |||
|---|---|---|---|---|---|---|---|---|
| +/+ | +/− | −/+ | −/− | |||||
| Influenza virus A | Total | 79 b | 0 | 29 | 248 | 73.2 (64.1, 80.61) | 100 (98.47, 100) | <0.001 |
| H1N1-2009 | 34 | 5 | 87.2 (73.29, 94.4) | 100 (98.8,100) | 0.0736 | |||
| H3N2 | 37 | 3 | 92.5 (80.14,97.42) | 100 (98.8,100) | 0.2482 | |||
| Untypeable | 7 | 21 | 25 (12.68, 43.36) | 100 (98.84,100) | <0.001 | |||
| Influenza virus B | 37 | 0 | 1 | 318 | 97.4 (86.5, 99. 53) | 100 (98.88, 100) | 1.0 | |
a
Four invalid Alere results were excluded from the statistical analysis, leaving a total of 356. +, positive; −, negative.
b
One FilmArray-negative sample was identified as influenza virus A by the Alere and confirmed by ProFLU+.