TABLE 1.
Comparison of three assays for HBV DNA detection and quantification
| Assay | Cobas Taq Man HBVa |
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|---|---|---|---|---|---|---|
| <6 IU/ml (17 samples) |
6–15 IU/ml (12 samples) |
Total (29 samples) |
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| No. (%) positive | Mean VL (range) in IU/ml | No. (%) positive | Mean VL (range) in IU/ml | No. (%) positive | Mean VL (range) in IU/ml | |
| Real Time Abbott | 15 (88.2) | 15.4 (10–24) | 12 (100) | 25.7 (10–46) | 27b (93.1) | 21.1 (10–46) |
| qHPCR | 11 (64.7) | 26.6 (4–52) | 10 (83.3) | 34.8 (6–77) | 21 (72.4) | 30.5 (4–77) |
| ddPCR | 6 (35.3) | 12 (8.6–18) | 8 (66.7) | 15.3 (7.7–40.4) | 14 (48.3) | 13. 9b (7.7–40.4) |
a
Proportions of positive samples and mean VLs were compared using Chi-square test and Student test, respectively.
b
Significant difference (P < 0.05).