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. 2014 Nov;52(11):4058–4062. doi: 10.1128/JCM.02400-14

TABLE 3.

Performance of rapid antimicrobial susceptibility testing of Gram-positive cocci (n = 68)

Antimicrobial agent (n) No. of isolate-antibiotic combinations No. of isolates that werea:
No. (%) of errors
Categorical agreement (%) Essential agreement (%)
Resistant Susceptible Very major Major Minor
Staphylococcus spp. (48) 872 275 586 4 (1.5) 2 (0.3) 0 99.3 99.0
    Penicillin G 48 42 6 100 100
    Oxacillin 48 30 18 100 97.9
    Clindamycin 48 22 26 100 100
    Erythromycin 48 30 18 100 100
    Levofloxacin 48 25 23 100 100
    Moxifloxacin 48 15 23 100 100
    Gentamicin 48 19 29 100 100
    Tobramycin 48 23 25 100 100
    Vancomycin 48 0 48 100 100
    Teicoplanin 48 7 41 2 1 93.8 89.6
    Linezolid 48 0 48 100 97.9
    Tetracycline 48 18 29 1 97.9 97.9
    Tigecycline 48 0 48 100 100
    Trimethoprim-sulfamethoxazole 48 17 31 100 100
    Fusidic acid 48 9 39 1 1 95.8 97.9
    Fosfomycin 48 14 34 100 100
    Rifampin 48 4 44 100 100
    Nitrofurantoin 48 0 48 100 100
    Mupirocin 8 0 8 100 100
Enterococcus spp. (17) 238 91 144 1 (1.1) 0 1 (0.4) 99.2 98.7
    Penicillin G 17 13 4 100 94.1
    Ampicillin 17 10 7 100 100
    Ampicillin-sulbactam 17 13 4 100 100
    Imipenem 17 10 7 100 100
    Erythromycin 17 14 0 1 94.1 94.1
    Levofloxacin 17 10 7 100 100
    Vancomycin 17 1 16 100 100
    Teicoplanin 17 1 16 100 100
    Linezolid 17 1 16 100 100
    Tetracycline 17 8 9 100 100
    Tigecycline 17 0 17 100 100
    Trimethoprim-sulfamethoxazole 17 0 17 100 100
    Quinupristin-dalfopristin 17 6 11 100 100
    Nitrofurantoin 17 4 13 1 94.1 100
Total Gram-positive cocci (68) 1,163 377 767 6 (1.6)b,c 2 (0.3)b 1 (0.1)b 99.2b 99.1b,c
a

The number of results within the intermediate category can be calculated by subtracting the resistant and susceptible results from the number of isolate-antibiotic combinations tested.

b

Streptococci (S. pneumoniae, n = 2 and S. agalactiae, n = 1) are included in the total number of Gram-positive cocci and in the calculation of the error and agreement rates for all Gram-positive cocci. No separate calculation of error and agreement rates was performed for streptococci because of the small number of isolates.

c

One VME (tetracycline in a S. pneumoniae isolate) and no other errors were observed in streptococci. Essential agreement (EA) was observed for all streptococcal isolate-antibiotic combinations.