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. 2014 Nov;52(11):4017–4019. doi: 10.1128/JCM.01848-14

TABLE 2.

P. jirovecii DHPS and DHFR mutations in 25 HIV-infected patients with P. jirovecii pneumonia in Guangzhou, China

No. of patients DHPS gene nucleotide(s) at positiona:
DHFR gene nucleotide(s) at positiona:
163 169 188 312
8b A C A T
4 A C A C
9 A C A T and Cc
1 A C A and Gc C
2 A and Gc C and Tc A T
1 A C and Tc A T and Cc
a

Relative to the full-length DHPS and DHFR genes of P. jirovecii (GenBank accession no. AF139132 and AF090368, respectively).

b

Wild type for DHPS and DHFR genes.

c

Confirmed by sequencing of plasmid clones. Double mutations were present in at least 3 clones for each patient.