TABLE 3.
Results of in vitro antifungal susceptibility testing of the 16 clinical isolates of Ochroconis spp. included in the study
| Species (no. of isolates tested) | GM or MIC dataa | MIC or MEC (μg/ml) forb: |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| AMB | ITC | PSC | VRC | AFG | CFG | MFG | TBF | ||
| O. mirabilis (11) | GM | 28.36 | 7.00 | 18.23 | 11.09 | 3.93 | 7.90 | 0.22 | 0.03 |
| MIC range | 8–32 | 1–32 | 0.5–32 | 2–32 | 0.015–32 | 1–32 | 0.06–0.5 | 0.015–0.125 | |
| MIC90 | 32 | 32 | 32 | 32 | 4 | 4 | 0.25 | 0.02 | |
| O. cordanae (1) | GM | 16 | 1 | 2 | 4 | 0.03 | 2 | 0.125 | 0.015 |
| O. olivacea (1) | GM | 32 | 1 | 1 | 4 | 0.03 | 1 | 0.125 | 0.015 |
| O. ramosa (3) | GM | 10.66 | 1 | 11.08 | 2.1 | 0.051 | 1 | 0.16 | 0.015 |
| MIC range | 8–16 | 1 | 0.25–32 | 0.5–4 | 0.015–0.125 | 1 | 0.125–0.25 | 0.015 | |
| Overall (16) | GM | 24.5 | 5.13 | 14.80 | 8.53 | 2.72 | 5.67 | 0.2 | 0.02 |
| MIC range | 8–32 | 1–32 | 0.25–32 | 0.5–32 | 0.02–32 | 1–32 | 0.06–0.50 | 0.02–0.13 | |
| MIC90 | 32 | 2 | 32 | 16 | 4 | 8 | 0.25 | 0.02 | |
a
GM, geometric mean.
b
MEC, minimal effective concentration; AMB, amphotericin B; ITC, itraconazole; PSC, posaconazole; VRC, voriconazole; AFG, anidulafungin; CFG, caspofungin; MFG, micafungin; TBF, terbinafine.