TABLE 3.

Results of IHC staining of tissues for the presence of CCoV antigen and other findings in puppies investigated in this study^a

Case	ID	CCoV IHC			Other finding(s)
		SI	LI	Other tissues
1	09-149076	Pos.	Neg.	Neg.: lung, kidney, bone marrow	Peyer's patch lymphoid depletion
2	09-89334	Pos.	Neg.	Neg.: lung, urinary bladder	Protein-losing enteropathy, Isospora species, Peyer's patch lymphoid depletion, aspiration pneumonia
3	09-97736	Pos.	Neg.	Neg.: lung, liver	Jejunoileal intussusception, Peyer's patch lymphoid depletion
4a	09-107207	Pos.	NA	NA	Canine parvovirus enteritis, AEEC
4b	09-110089	Pos.	Neg.	Neg.: lung, MLN	Trichomoniasis, Peyer's patch lymphoid depletion, bronchointerstitial pneumonia
5	09-123567	Pos.	Neg.	Neg.: thymus, heart, trachea, lung, liver, pancreas, spleen	AEEC, Cystoisospora ohioensis, aspiration pneumonia
6a	10-51534A	Pos.	Neg.	Pos.: MLN (rare); Neg.: thymus, lung, stomach, pancreas	AEEC, aspiration pneumonia, bone marrow depletion, thymic and MLN lymphoid depletion
6b	10-51534B	Pos.	Neg.	Pos.: MLN (rare); Neg.: thymus, lung	AEEC, bronchopneumonia, bone marrow depletion, thymic, MLN and Peyer's patch lymphoid depletion
7	12-120628	Pos.	Neg.	Neg.: lung, tongue, stomach, MLN, liver, gallbladder, pancreas, kidney	Jejunojejunal intussusception, ulcerative gastritis, Peyer's patch lymphoid depletion, aspiration pneumonia
8	12-159396	Pos.	Pos.	Neg.: thymus, lung, liver, stomach, spleen, kidney	Mild, multifocal, acute hepatocellular necrosis
9	13-47387	Pos.	Pos.	Pos.: MLN (rare); Neg.: lung, stomach	Peyer's patch lymphoid depletion, mild, multifocal, subacute hepatocellular necrosis

^aSI, small intestine; LI, large intestine; Pos., positive; Neg., negative; NA, not available; MLN, mesenteric lymph node; AEEC, attaching-effacing Escherichia coli.