TABLE 2.
Laboratory performance levels of three rapid diagnostic tests for the dual detection of HIV and T. pallidum antibodies, compared to reference methodsa
| RDT | HIV antibody |
T. pallidum antibody |
||
|---|---|---|---|---|
| % sensitivity (95% CI) | % specificity (95% CI) | % sensitivity (95% CI) | % specificity (95% CI) | |
| SD Bioline | 97.9 (92.0–99.6) | 100 (91.5–100) | 93.0 (84.8–97.1) | 100 (92.9–100) |
| ChemBio | 98.9 (93.6–99.9) | 98.1 (88.6–99.9) | 95.3 (87.9–98.5) | 100 (92.9–100) |
| MedMira | 97.9 (92.0–99.6) | 94.2 (83.1–98.5) | 94.1 (86.3–97.8) | 96.9 (88.2–99.5) |
a
The reference HIV antibody method was the Siemens Advia Centaur HIV 1/O/2 enzyme immunoassay and the GS HIV-1 Western blot kit, and the T. pallidum antibody reference method was the Serodia TP-PA method.