. Author manuscript; available in PMC: 2015 Feb 2.

Published in final edited form as: J Infect Dis. 2011 Apr 15;203(8):1192–1199. doi: 10.1093/infdis/jiq166

Table 2. Cellular Immune Responses to Merozoite Surface Protein 5 and Purified Protein Derivative.

		AC	Pf	Pv	P value^#	P value^*
Proliferation^a	n	10	28	10
	Media [cpm]	394 [129–2371]	381 [189–828]	685 [375–1535]	.87	.08
	MSP5 [cpm]	488 [144–1616]	691 [230–1134]	1292 [653–2857]
	MSP5 [SI]	1 [0.8–1.5]	1.9 [0.8–4.9]	1.3 [1–7.7]	.14	.92
	PPD [cpm]	5274 [219–11,485]	6770 [1427–19,062]	22,124 [7128–49,498]
	PPD [SI]	5 [1–28]	13 [5–25]	16 [10–68]	.18	.36
IFN-γ^b	n	7	19	12
	Media	0 [0–10]	5 [0–20]	9 [3–39]	.09	.4
	MSP5	0 [0–45]	20 [10–38]	49 [26–75]	.16	.01
	PPD	38 [0–200]	10 [3–33]	136 [77–271]	.77	.04
T-cell frequency^c	n	10	22	12
	CD3+	54 [29–70]	57 [44–60]	57 [54–64]	0.8	0.3

NOTE. AC, asymptomatic malaria-exposed; Pf, acute P. falciparum malaria; Pv, acute P. vivax malaria; IFN, interferon; MSP5, merozoite surface protein 5; PPD, purified protein derivative; SI, stimulation index.

Data expressed as median cpm or SI [interquartile range (IQR)]

Data expressed as median SFU/million [IQR]

expressed as % of peripheral blood mononuclear cells [IQR];

Mann-Whitney U test AC vs Pf;

Mann-Whitney U test Pf vs Pv.