Table 1.
Small Molecules/Growth Factors and the Target Pathways for Their Action
| Small molecules/growth factors | Target pathway | Activator/inhibitor |
|---|---|---|
| SB431542 | TGFβ | Inhibitor |
| A-83-01 | TGFβ | Inhibitor |
| Activin | TGFβ | Activator |
| PD0325901 | FGF/Erk | Inhibitor |
| CHIR99021 | GSK3β | Inhibitor |
| Kenpaullone | GSK | Inhibitor |
| LIF | JAK/STAT3 | Activator |
| BMP4 | BMP | Activator |
TGF, transforming growth factor; FGF, fibroblast growth factor; Erk, extracellular signal-regulated kinases; GSK, glycogen synthase kinase; JAK, janus kinase; STAT, signal transducer and activator of transcription; BMP, bone morphogenetic protein; LIF, leukemia inhibitor factor.