Table 1.
Characteristics of included studies focused on protein expression of endostatin.
| First author | Year | Country | Sample size | Gender (M/F) | Age (years) | Method | CASP | |||
|---|---|---|---|---|---|---|---|---|---|---|
| Case | Control | Case | Control | Case | Control | |||||
| Wang [36] | 2011 | China | 100 | 30 | 68/32 | 20/10 | 57.2 ± 12.4 | 57.2 ± 12.4 | ELISA | 8 |
| Masiak [10] | 2011 | Poland | 20 | 10 | — | — | — | — | ELISA | 5 |
| Yuan [38] | 2010 | China | 82 | 24 | 56/26 | 16/8 | 59 (27~84) | 59 (27~84) | ELISA | 8 |
| Yang [37] | 2010 | China | 60 | 30 | 34/26 | 28/12 | 38~76 | 32~68 | ELISA | 7 |
| Liu [34] | 2009 | China | 60 | 30 | 37/23 | 17/13 | 53.3 ± 8.2 | 38.3 ± 7.8 | ELISA | 7 |
| Li [24] | 2009 | China | 52 | 52 | 33/19 | 33/19 | 62 (38~75) | 62 (38~75) | ELISA | 6 |
| Ding [32] | 2008 | China | 50 | 25 | 30/20 | — | 62 (30~85) | — | EIA | 6 |
| Li [33] | 2007 | China | 36 | 30 | 23/13 | 19/11 | 58.7 ± 7.9 | 58.7 ± 7.9 | ELISA | 6 |
| Wang [35] | 2006 | China | 67 | 33 | 37/30 | 19/14 | 48 (35~73) | 46 (31~69) | ELISA | 7 |
| Huang [23] | 2006 | China | 72 | 33 | 38/34 | 19/14 | 48 (35~73) | 46 (31~69) | ELISA | 8 |
| Woo [22] | 2006 | Korea | 107 | 23 | 70/37 | 15/8 | 60 (31~78) | 58 (34~75) | ELISA | 8 |
| Koç [39] | 2006 | Turkey | 30 | 30 | 10/20 | 11/19 | 41.3 ± 16.7 | 64.3 ± 16.7 | EIA | 6 |
M: male; F: female; ELISA: enzyme-linked immunosorbent assay; CASP: critical appraisal skills program.