Depressed patients' mean score of suicidal ideationa and HDRS-24 factorsb by study week and treatment with paroxetine vs bupropionc
footnotes:
aSuicidal ideation measured using the Beck Scale for Suicidal Ideation.
bHDRS-24 factor content:
Psychic Depression = Depressed mood + Guilt + Retardation + Helplessness + Hopelessness + Worthlessness.
Loss of Motivation = Work/activities+ Appetite + Libido + Weight loss.
Disturbed Thinking = Lack of insight + Depersonalization/derealization + Paranoia + Obsessions/compulsions.
Anxiety = Agitation + Psychic anxiety + Somatic anxiety + Hypochondriasis.
Sleep = Insomnia early + Insomnia middle + Insomnia late.
cError bars represent standard error of the mean. Paroxetine (N=36) and bupropion (N=38) sample sizes decreased over time due to drop-out (see Table 1).