Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jan 19;2015:342984. doi: 10.1155/2015/342984

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015 Valentina Cottignoli et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

SEM analysis of pathological biomineralization morphology. (a) Agglomeration of variably sized (micrometer range) calcified nanoparticles, indicated by the arrows (12000x, mitral valve sample). (b) Agglomeration of spherical calcified nanoparticles in a framework of organic filaments (bicuspid aortic valve sample), formed by extracellular matrix proteins. (c) Magnified view (25000x) of individual spherical nanoparticle along a mineralized filament, indicated by the arrow (mitral valve sample). (d) Agglomeration of spherical calcified nanoparticles in the nanometer range at 40000x; the smallest measured nanoparticle was 262.7 nm in diameter (bicuspid aortic valve sample).