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. 2015 Feb 2;6:9. doi: 10.3389/fimmu.2015.00009

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Copyright © 2015 Dias, Castelli, Collares, Moreau and Donadi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Variation sites at the 5′ upstream regulatory region (5′URR) of the HLA-G gene (1.4 kb upstream of ATG), as well as the target binding sites of the described transcriptional factors. The position of the variation sites is determined in relation to Adenine of the initiation codon ATG. *Since there is no official nomenclature for 5′URR haplotypes, they were designed as previously reported (10). Transcription factors: CREB1, CAMP responsive element binding protein 1; ATF1, cyclic AMP-dependent transcription factor ATF-1; RREB1, Ras responsive element binding protein 1; IRF1, interferon regulatory factor 1; p50, nuclear factor NF-κ-B p105 subunit; RFX5, DNA-binding protein RFX5 (RFX family); PR, progesterone receptor. I, insertion of a guanine at position −540; Δ, deletion of an adenine at position −533.