Table 1.

Example of stressors distribution.

	Mon	Tue	Wed	Thu	Fri	Sat	Sun
Week 1	BW hot drier	Shaking	Restraint	Social defeat	Restraint	Restraint	Tilted cage
Week 2	BW restraint	Shaking	Social defeat	Restraint	Shaking	Social defeat	Restraint
Week 3	BW restraint	Social defeat	Restraint	BC-zenith	Social defeat	Restraint	Shaking
Week 4	BW	EPM	FST	Shaking	Restraint	Shaking	Hot drier
	BC – nadir	OF	TST
	Social defeat	Restraint	Social defeat
Week 5	BW restraint	Sacrifice 4 weeks tilted cage	Cytometry hot drier	Restraint	Social defeat	Inverted light	Inverted light
Week 6	BW hot drier	Shaking	Restraint	Inverted light	Overnight illumination	Restraint	Hot drier
Week 7	BW restraint	Social defeat	Restraint	BC-zenith	Shaking	Restraint	Overnight illumination
Week 8	BWBC-nadir	EPM OF Restraint	FST TST Social defeat	MWM shaking	MWM restraint	MWM restraint	MWM shaking
Week 9	BW	Sacrifice 8 weeks	Cytometry

BW, body weight measurement; BC, blood collection; EPM, elevated-plus maze; OF, open field; FST, forced swimming test; TST, tail-suspension test; MWM, Morris water maze test.