Figure 3.

Approach-1(b) Graph based interaction transfer. The big circles show the two protein complexes found to be enriched by Network Blast : the Arabidopsis protein complex on the left, and the human protein complex on the right. The edges within a protein complex are the PPIs within the host organism. The edges connecting the two protein complexes (i.e., the two circles) are the homology edges. The solid line connecting sipA with a human protein node is a bootstrap interaction. We use this to infer the new plant-Salmonella interaction indicated by the dotted line.