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. 2015 Feb 2;6:31. doi: 10.3389/fimmu.2015.00031

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Copyright © 2015 Horton and Mathew.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Mechanism by which tumor cells may inhibit natural cytotoxicity through NCR recognition by DAMPs. The association of DAMPs with HSPGs, HLA I, or other potential co-ligands may form larger complex ligands for the members of the NCR family.