Table 1.

Pharmacological potential of Indigofera suffruticosa.

Scientific account	Related compounds
Gastroprotective agent acute ulcer stimulating prostaglandin, mucus and HSP70. (Luiz-Ferreira et al., 2011)	Ethyl acetate fraction from methanolic extract showed the best action and the authors highlighted the role of role of flavonoids and alkaloids presents in AcF as active compounds
In vivo action against Pediculosis capitis (García Calixto et al., 2011)	An effective treatment using 5% I. suffruticosa Mill tincture was reported in a patient infested with Pediculosis capitis
Immunostimulatory and antitumoral actvities in vitro (Lopes et al., 2011)	This study evaluated the action of both alkaloid fraction and pure indigo. Indigo showed high activity which suggest that it is the major active principle in I. suffruticosa
Antimycobacterial (Carli et al., 2010)	These authors did not isolate or detected any compounds. The methanolic extract showed better activity than dichloromethane
Anticonvulsant effect (Almeida et al., 2013)	Alkaloids, flavonoids, steroids, proteins, carbohydrates, indigo carmine and essential oils (Linalool and Pinene) were detected in the methanolic extract
Anti-inflammatory property in vivo (Chen et al., 2013a)	Eight phenolic compounds were quantified: salicylic acid, syringic acid (major compounds) ρ-coumaric acid, vanillin, syringaldehyde, quercetin, isoliquiritigenin, formononetin. Salicylic acid was found in the plasma of mice fed with I. suffruticosa extracts
In vivo increase of Phase II detoxification enzyme and glutathione levels (Chen et al., 2013b)	The authors reported the same compounds quantified by Chen et al. (2013a). Ethanolic extracts showed the best action on the induction of phase II detoxification enzyme, and syringic acid was the most active among phenolic compounds detected, however, it was less potent than ethanolic extracts