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. Author manuscript; available in PMC: 2015 Feb 2.
Published in final edited form as: Biochemistry (Mosc). 2011 Nov;76(11):1262–1269. doi: 10.1134/S0006297911110083

Fig. 1.

Fig. 1

Schematic representation of cortactin and cortactin mutants. The 1653 bp cortactin cDNA encodes a protein consisting of an amino-terminal acidic domain (NTA), a repeat region (RR), a helical region (HR), a proline-rich region (PRR), and a Src homology 3 (SH3) domain. The following derivatives were studied: mutant 1 (M1), with a deletion of the RR, HR, PRR, and SH3 domain; mutant 2 (M2), with a deletion of the NTA and RR; mutant 3 (M3), with a deletion of RR; mutant 4 (M4), with a deletion of the SH3 domain; and mutant 5 (M5), with a deletion of PRR and the SH3 domain. Δ, deletion; N, N terminus; C, C terminus.