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Yki induces Sd-dependent JNK activation. Knocking down sd suppressed Yki-induced JNK activation. Third instar wing discs were stained for MMP1. YkiS168A-induced MMP1 up-regulation (A) is suppressed by expression of sd RNAi (B), but not that of mad RNAi (C and D). Genotype: ptc > YkiS168A + LacZ (A), ptc > YkiS168A + sd RNAi (B), ptc > YkiS168A + mad RNAi (C), and ptc> mad RNAi (D). See also Figs. S8 and S9.
